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Editorial, JCMS Vol. 1(2)

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I am delighted with the response received from our inaugural issue of the Journal of Cutaneous Medicine and Surgery. We have an excellent second issue and have already received numerous articles for inclusion in the next issue. A number of themes are again included in this issue. Reflecting our aim of reporting state-of-the-art issues in cutaneous biology and in dermatology, we have insightful articles in both the basic and clinical sections.

In the initial article, Dr. Krueger focuses on the ability to analyze from hair agents that are absorbed from the environment. Although presently not being utilized in general dermatology, this could have a significant impact on a forensic biology or toxicology program and may, in fact, lead to clinical diagnostic assessments in the future. Chen and co-workers examine some of the immunoregulatory properties of retinoic acid by examining the effect on two important cytokines in the skin, IL-12 and IL-10, in Langerhans' cells and keratinocytes.

On a clinical note, Wasti et al. focus on an important issue of the anatomic distribution of melanoma. It is known that intermittent sunburns have been implicated in a causative role in cutaneous melanoma. They conclude that, since the anatomic distribution of painful sunburns is similar in men and women, whereas the anatomic distribution of melanomas differs, it appears that factors other than direct UV damage contribute to the anatomic distributions.

In our Point­Counterpoint editorials, we have an excellent dialogue by Drs. Woodley and Gammon on the joys of academia and of private practice, respectively. This is particularly pertinent in that, early in his career, Dr. Gammon was a role model to many for academic dermatology and is now experiencing the joys of private practice. Academics and private practitioners should find this dialogue of interest.

Our Continuing Medical Education section includes an initial article by Dr. Sherri Bale. Dr. Bale will be reviewing a series of articles on genetics in dermatology in the Critical Appraisal series. This will be an ongoing series, which I feel both practitioners and investigators will find useful.

One of the most exciting developments in medicine in the past decade has been the potential for gene therapy. Dr. Hope reviews recent advances in gene therapy and its potential application in dermatology.

While we enjoyed the lovely weather of summer and are enjoying the still warm fall weather, winter is around the corner, and the timely article by Drs. Kim and colleagues reviews the area of cold-induced disorders.

I believe that our first two issues of the Journal of Cutaneous Medicine and Surgery have established a means of communication for addressing important developments in research and education in dermatology. We look forward to the continuing support from our colleagues at the forefront of dermatologic research and clinical medicine.

Daniel N. Sauder
Editor in Chief
Division of Dermatology
University of Toronto

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